A team of South African doctors in the capital city Pretoria has been hailed as pioneers in the field of global medicine after performing the first-ever transplant of a patient’s middle ear.
The achievement–which used 3D-printed technology to reconstruct the broken bones of a middle ear–is being celebrated as a long-term solution to conductive hearing loss. What’s more, the surgery can be performed on people of any age, including newborn babies, curing patients of a form of deafness that is caused by physical damage or infection in the middle ear as well as congenital birth defects and metabolic diseases.
The first patient to undergo the procedure was a 35-year-old male who lost his hearing after a car accident devastated his middle ear. Due to the nature of his trauma, the operation lasted about an hour and a half, according to Legit.
The brains behind the medical team at the University of Pretoria’s Steve Biko Academic Hospital, Professor Mashudu Tshifularo, had been studying conductive hearing loss over the past decade, but in the past two years he began investigating the use of 3D printing technologies for the purpose of scanning and wholly recreating the smallest bones, or ossicles, of the middle ear–namely the hammer, anvil and stirrup.
In a celebratory press release issued by the South African Department of Health, Tshifularo is quoted as explaining:
“By replacing only the ossicles that aren’t functioning properly, the procedure carries significantly less risk than known prostheses and their associated surgical procedure.
We will use titanium for this procedure, which is biocompatible. We use an endoscope to do the replacement, so the transplant is expected to be quick, with minimal scarring.”
Tshifularo told local radio station Jacaranda FM:
“This was one of our patients we have been waiting for, for this reconstruction for almost three years now because they are not affordable … [but] we have done something new in the world and people will remember us for that.”
[WATCH] A pioneering surgical procedure using 3D-printed middle ear bones, developed by Professor Mashudu Tshifularo and his team at the University of Pretoria (UP) Faculty of Health, may be the answer to conductive hearing loss, a middle ear problem caused by congenital birth defects, infection, trauma or metabolic diseases.
Posted by Gauteng Health Department on Wednesday, March 13, 2019
While expressing pride that he was the first in the world to revolutionize the new approach to address hearing loss, Tshifulara remains steadfast that the treatment must eventually become accessible and affordable for poor and working-poor patients, such as those who use South Africa’s public hospitals.
“Because we are doing it in the country and we are going to manufacture here, it has to be affordable for our people in state hospitals.
It will be very accessible because as long as we can train the young doctors to be able to do this operation, then it will be accessible for them as well.”
For Tshifularo, “innovate or perish” sums up his approach to medical science–both in terms of education, research, invention and clinical procedures, and also in terms of devising new solutions to the array of problems faced by struggling communities.
He hopes that he and his team at the university’s Department of Otorhinolaryngology (Ear, Nose and Throat) will receive the necessary funding from the government and private sponsors to ensure that this innovative approach to hearing loss treatment can get off the ground.
South African Minister of Health Aaron Motsoaledi has already pledged that the Department of Health will “do everything in our power to assist and mobilize resources to make sure that Prof. Tshifularo gets all the help he needs for this far-reaching innovation.”
Pollution Is Making Human Penises Shrink and Causing a Collapse of Fertility, Scientists Say
With many still scoffing at the idea of rampant pollution posing a threat to humanity, a new study could drastically change the conversation: the chemicals across our environment could be the cause of shrinking human penises.
According to a new book by Dr. Shanna H. Swan, conditions in the modern world are quickly altering the reproductive development of humans and posing a threat to our future as a species.
The argument is laid out in her new book Count Down: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race.
The book discusses how pollution is not only leading to skyrocketing erectile dysfunction rates and fertility decline, but also an expansion in the number of babies born with small penises.
While it may seem like good fodder for jokes, the research could portend a grim future for humanity’s ability to survive.
Swan co-authored a study in 2017 that found sperm counts had precipitously fallen in Western countries by 59 percent between 1973 and 2011. In her latest book, Swan blames chemicals for this crisis in the making.
“Chemicals in our environment and unhealthy lifestyle practices in our modern world are disrupting our hormonal balance, causing various degrees of reproductive havoc,” she wrote in the new book.
“In some parts of the world, the average twentysomething woman today is less fertile than her grandmother was at 35,” she also wrote, noting that men could have only half the sperm count of their grandfathers.
Swan blames the disruption on phthalates, the chemicals used in plastic manufacturing that also have an impact on how the crucial hormone endocrine is produced
However, experts note that the proper implementation of pollution reduction measures could help humanity prevent the collapse of human fertility.
Visualizing The World’s Deadliest Pandemics By Population Impact
Humanity has been battling against disease for centuries.
And while most contagious outbreaks have never reached full-blown pandemic status, Visual Capitalist’s Carmen Ang notes that there have been several times throughout history when a disease has caused mass devastation.
Here’s a look at the world’s deadliest pandemics to date, viewed from the lens of the impact they had on the global population at the time.
Editor’s note: The above graphic was created in response to a popular request from users after viewing our popular history of pandemics infographic initially released a year ago.
Death Toll, by Percent of Population
In the mid-1300s, a plague known as the Black Death claimed the lives of roughly 200 million people – more than 50% of the global population at that time.
Here’s how the death toll by population stacks up for other significant pandemics, including COVID-19 so far.
The specific cause of the Black Death is still up for debate. Many experts claim the 14th-century pandemic was caused by a bubonic plague, meaning there was no human-to-human transmission, while others argue it was possibly pneumonic.
Interestingly, the plague still exists today – however, it’s significantly less deadly, thanks to modern antibiotics.
History Repeats, But at Least We Keep Learning
While we clearly haven’t eradicated infection diseases from our lives entirely, we’ve at least come a long way in our understanding of what causes illness in the first place.
In ancient times, people believed gods and spirits caused diseases and widespread destruction. But by the 19th century, a scientist named Louis Pasteur (based on findings by Robert Koch) discovered germ theory – the idea that small organisms caused disease.
What will we discover next, and how will it impact our response to disease in the future?
Like this? Check out the full-length article The History of Pandemics
Republished from ZH with permission.
California Bill Backed by PTSD War Veterans Groups Would Legalize Psychedelics Statewide
California could soon decriminalize psychedelics statewide if one legislator’s new bill is passed, marking another step by the Golden State to do away with laws seen by critics as antiquated vestiges of the failed U.S. war on drugs.
On Thursday, Senator Scott Wiener of San Francisco introduced Bill 519, which would comprehensively decriminalize the use of and possession of psychedelics, following the lead of such places as Oakland, Santa Cruz, the District of Columbia, and Oregon, which have all decriminalized the drugs to varying degrees.
Under the proposed law, a range of psychedelic drugs including psilocybin – the hallucinogen in “magic” mushrooms – psilocyn, 3,4-MDMA (also known as molly or ecstasy), LSD, ketamine, DMT, ibogaine, and mescaline would all be decriminalized. Like a previous law passed in 2018 that expunged cannabis-related convictions from the records of Californians, Bill 519 would also wipe clean prior convictions for the use or possession of drugs.
While the comprehensive decriminalization measure would open the door to any sort of use of the drugs, not limited to medical, it would also be tied to measures that endorse the medicinal and therapeutic benefits of psychedelics which have gained increased recognition from health experts and researchers in recent years.
“Given the severity of our mental health crisis, we shouldn’t be criminalizing people for using drugs that have shown significant promise in treating mental health conditions,” Wiener said in a statement. “People should be able to seek alternative treatment for diseases like anxiety, depression, and PTSD, and we need to make science-based treatments available to those in need.”
The bill has also been heavily supported by two groups, the Heroic Hearts Project and VETS (Vets Exploring Treatment Solutions), both nonprofit organizations that assist veterans in addressing mental health challenges stemming from trauma, such as PTSD.
The strategy tout the medical benefits of the drugs is one that has been used with success in past efforts by drug policy reform advocates.
“That’s how it worked with cannabis,” Oregonian drug policy reform advocate Anthony Johnson told the Guardian. Johnson helped lead efforts in his state to decriminalize the possession of small amounts of basically all illicit drugs through Measure 110, which voters overwhelmingly approved in November.
“It’s definitely a way to help people that need it first and foremost, but also then to educate the public about these substances of how the drug war has been a failed policy and how there is a better approach,” Johnson added.
In the case of Oregon’s Measure 109, which cleared the way for the all-out legalization of psilocybin mushrooms, petitioners highlighted the need to end the prohibition of the substance as a means toward treating mental health challenges through alternative methods.
“Healthcare professionals, veterans, mothers, people struggling with depression, anxiety, addiction and end of life distress, community organizations, and so many others answered to call for a new option to help so many who are suffering,” a coalition of Oregon advocates said in a statement last November following voters’ overwhelming approval of the legal psilocybin therapy bill.
As has been the case in other states, however, the largest obstacle to decriminalization has been law enforcement, who cite concerns over public safety, and the private prison industry which enjoys generous profits from state contracts to incarcerate drug users. However, state Senator Wiener hopes that the testimony of veterans will help convince opponents of the need to shed their preconceptions and biases toward users of psychedelic drugs.
“There’s a stereotype of who’s using psychedelics, but it’s much broader than that and when you have veterans coming into the Capitol talking about how psychedelics help them with PTSD and help them get their lives back, that’s incredibly powerful for legislators,” Wiener explained.
Among those veterans is 38-year-old veteran Juliana Mercer, who spent 16 years in the U.S. Marine Corps, including 10 years of active duty service over the course of one tour in Iraq and one in Afghanistan.
As a four-year member of the wounded warriors unit, Mercer saw unspeakable horrors that left an indelible impression on her psyche – ultimately resulting in long-term trauma that she was largely unable to address.
“I lost quite a few friends and just saw a lot of a lot of damage and destruction along the way,” Mercer said. “I put all of that stuff away and kind of forgot about it for a while, and once I slowed down it was all just sitting there and I didn’t know what to do with it.”
While her first experience with psychedelics was recreational, she eventually gained a sense of connectedness that had been absent for years. She eventually reached out to the Heroic Hearts Project a year and a half ago to undergo ayahuasca therapy, which she said had completely exceeded expectations in allowing her to release “years of grief.”
“I kept hearing that when you do some of these plant medicines, you’ll be able to do 10 years worth of work in one session,” Mercer explained. “Just one of my sessions really brought out all of that pain and the grief that I didn’t even know was in there and allowed me to just completely release it and expel it, things that I had no idea were there.”
For licensed clinical social worker Lauren Taus, therapies involving plants such as ayahuasca and psilocybin are simply strong tools rather than cure-alls for mental health challenges. However, with the ongoing pandemic compounding a mental health crisis that has long been felt across the United States, Taus is adamant that such potent tools must be decriminalized.
“The causes of trauma are multiplying way faster than the solutions,” Taus said. “Current treatment is generally not very effective.”
“Psychedelic medicine has been engaged with globally for eons,” she added. “This stuff works and we deserve to have access to solutions that will be sustainable.”
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