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Johns Hopkins Study Shows Broccoli Sprout Compound as Potential Schizophrenia Treatment

Sulforaphane may help those who experience schizophrenia and its symptoms.




Broccoli sprouts benefits
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Broccoli sprouts have long been used by health conscious individuals to help provide a wide range of nutrients to one’s diet and to provide quick energy. Broccoli sprouts are back in focus for a different reason and are being touted by one of the most prestigious medical schools in the world.

Researchers at Johns Hopkins Medicine have recently shown how sulforaphane, a compound found naturally in broccoli sprouts and other cruciferous vegetables, may help those who experience schizophrenia and its symptoms.  

To begin with their research, the researchers found that those experiencing psychosis had a statistically significant 4% lower amount of glutamate in their anterior cingulate cortex, as compared to healthy individuals. 

Glutamate is a brain chemical that sends signals between neurons and heightened activity of glutamate has been shown to be related to depression and schizophrenia. 

The researchers also found that there was a significant reduction in glutathione, one of the brain’s best antioxidants. What is interesting is that glutathione is made from three different compounds and one of these compounds is glutamate.

Sulforaphane comes into the picture because it turns on a gene that makes more of the enzyme that sticks glutamate with another molecule to end up making glutathione. Essentially, more sulforaphane results in more glutathione. 

When testing on rats, the researchers supplemented with the sulforaphane-created glutathione and found that the brains had slowed down their nerve cell firing and behaved much less like schizophrenic brain activity. 

The researchers believe that schizophrenic brains may carry less glutamate and thus, use it up more quickly. Supplementing sulforaphane on human schizophrenics is the next step to test its effectiveness and would be interesting to see the results of, given that it is very safe for human consumption. How effective could it actually be for human schizophrenics?

One medical doctor and psychiatrist who has extensive and impressive history treating schizophrenics is Dr. Abram Hoffer, who has used large doses of niacin, which is vitamin B3, and vitamin C on his patients. He has conducted several double-blind, placebo controlled human clinical trials, which can be read here. 

He is also the doctor who has used niacin and vitamin C to help alcoholics recover from addiction. 

In regards to schizophrenia, there are several other nutrients to consider. Combinations that would be worth further scientific study on schizophrenia might include NAC (N-acetyl cysteine), Sulforaphane and niacin, as well as combinations that include alpha lipoic acid and high doses of vitamin C. Looking at nutrients that increase SOD (superoxide dismutase) in the brain would also be worth further study. 

Check out the 3 minute video version of this information for a more comprehensive learning experience: 

What are your thoughts on this? Have you used broccoli sprouts or sulforaphane supplements to support your brain health? Do you know someone who might find this recent study interesting?

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Crystalline Nutrients creates 3 minute YouTube videos on the latest nutrition science research. Videos are meant to be short to allow busy health-conscious people and practitioners stay up to date with only a few minutes of their time. Follow Crystalline Nutrients on YouTube and Instagram for three new videos per week.


Biden to Ban Menthol Cigarettes, Citing Health Impact on Youth and Black People

Elias Marat



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The Biden administration is reportedly planning to propose an immediate ban on menthol cigarettes, a product that has long been targeted by anti-smoking advocates and critics who claim that the tobacco industry has aggressively marketed to Black people in the U.S.

On Wednesday, the Washington Post reported that the administration could announce a ban on menthol and other flavored cigarettes as soon as this week.

Roughly 85 percent of Black smokers use such menthol brands as Newport and Kool, according to the Food and Drug Administration. Research has also found that menthol cigarettes are easier to become addicted to and harder to quit than unflavored tobacco products, along with other small cigars popular with young people and African Americans.

Civil rights advocates claim that the decision should be greeted by Black communities and people of color who have been marketed to by what they describe as the predatory tobacco industry.

Black smokers generally smoke far less than white smokers, but suffer a disproportionate amount of deaths due to tobacco-linked diseases like heart attack, stroke, and other causes.

Anti-smoking advocates like Matthew L. Myers, president of Campaign for Tobacco-Free Kids, also greeted the move to cut out products that appeal to children and young adults.

“Menthol cigarettes are the No. 1 cause of youth smoking in the United States,” he said. “Eliminating menthol cigarettes and flavored cigars used by so many kids will do more in the long run to reduce tobacco-related disease than any action the federal government has ever taken.”

However, groups including the American Civil Liberties Group (ACLU) has opposed the move, citing the likelihood that such an action could lead to criminal penalties arising from the enforcement of a ban hitting communities of color hardest.

In a letter to administration officials, the ACLU and other groups including the Drug Policy Alliance said that while the ban is “no doubt well-intentioned” it would also have “serious racial justice implications.”

“Such a ban will trigger criminal penalties, which will disproportionately impact people of color, as well as prioritize criminalization over public health and harm reduction,” the letter explained. “A ban will also lead to unconstitutional policing and other negative interactions with local law enforcement.”

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Pollution Is Making Human Penises Shrink and Causing a Collapse of Fertility, Scientists Say

Elias Marat



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With many still scoffing at the idea of rampant pollution posing a threat to humanity, a new study could drastically change the conversation: the chemicals across our environment could be the cause of shrinking human penises.

According to a new book by Dr. Shanna H. Swan, conditions in the modern world are quickly altering the reproductive development of humans and posing a threat to our future as a species.

The argument is laid out in her new book Count Down: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race.

The book discusses how pollution is not only leading to skyrocketing erectile dysfunction rates and fertility decline, but also an expansion in the number of babies born with small penises.

While it may seem like good fodder for jokes, the research could portend a grim future for humanity’s ability to survive.

Swan co-authored a study in 2017 that found sperm counts had precipitously fallen in Western countries by 59 percent between 1973 and 2011. In her latest book, Swan blames chemicals for this crisis in the making.

“Chemicals in our environment and unhealthy lifestyle practices in our modern world are disrupting our hormonal balance, causing various degrees of reproductive havoc,” she wrote in the new book.

“In some parts of the world, the average twentysomething woman today is less fertile than her grandmother was at 35,” she also wrote, noting that men could have only half the sperm count of their grandfathers.

Swan blames the disruption on phthalates, the chemicals used in plastic manufacturing that also have an impact on how the crucial hormone endocrine is produced

However, experts note that the proper implementation of pollution reduction measures could help humanity prevent the collapse of human fertility.

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Visualizing The World’s Deadliest Pandemics By Population Impact

Elijah Cohen



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Humanity has been battling against disease for centuries.

And while most contagious outbreaks have never reached full-blown pandemic status, Visual Capitalist’s Carmen Ang notes that there have been several times throughout history when a disease has caused mass devastation.

Here’s a look at the world’s deadliest pandemics to date, viewed from the lens of the impact they had on the global population at the time.

Editor’s note: The above graphic was created in response to a popular request from users after viewing our popular history of pandemics infographic initially released a year ago.

Death Toll, by Percent of Population

In the mid-1300s, a plague known as the Black Death claimed the lives of roughly 200 million people – more than 50% of the global population at that time.

Here’s how the death toll by population stacks up for other significant pandemics, including COVID-19 so far.

The specific cause of the Black Death is still up for debate. Many experts claim the 14th-century pandemic was caused by a bubonic plague, meaning there was no human-to-human transmission, while others argue it was possibly pneumonic.

Interestingly, the plague still exists today – however, it’s significantly less deadly, thanks to modern antibiotics.

History Repeats, But at Least We Keep Learning

While we clearly haven’t eradicated infection diseases from our lives entirely, we’ve at least come a long way in our understanding of what causes illness in the first place.

In ancient times, people believed gods and spirits caused diseases and widespread destruction. But by the 19th century, a scientist named Louis Pasteur (based on findings by Robert Koch) discovered germ theory – the idea that small organisms caused disease.

What will we discover next, and how will it impact our response to disease in the future?

Like this? Check out the full-length article The History of Pandemics

Republished from ZH with permission.

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