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Scientists Infect Monkeys With Coronavirus in Search of a Cure for COVID-19

The monkeys who took part in the experiment were euthanized shortly after the study was completed.

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Monkeys Coronavirus

(TMU) — While many people around the world have just recently become familiar with the term “coronavirus,” it is a classification that describes a number of different illnesses which range in severity from the common cold, to the newly discovered COVID-19 novel coronavirus that has dominated international headlines over the past month.

Researchers around the world are taking different approaches to develop a possible cure or vaccine for the illness as it continues to quickly spread across the planet.

A controversial approach taken by scientists at the US National Institutes of Health (NIH) was detailed in a study published earlier this month in the journal PNAS.

In the study, 18 rhesus macaque monkeys were intentionally infected with the MERS-CoV coronavirus, also known as the Middle East respiratory syndrome. MERS is one of the most deadly strains of coronavirus, and has been known to pneumonia, fever and even organ failure. However, human to human transmission is far less common with the MERS strain than we have seen with the new COVID-19 strain, so it is far less contagious.

Researchers treated the infected monkeys with an experimental vaccine called remdesivir, which has been shown to be effective for multiple different coronavirus strains.

The researchers found that the experimental drug was also effective at treating the monkeys in their study that were infected with MERS. This has led the team to conclude that this drug could be effective at treating the new COVID-19 coronavirus strain.

The conclusion of the study stated that “Taken together, the data presented here on the efficacy of remdesivir in prophylactic and therapeutic treatment regimens, the difficulty of coronaviruses to acquire resistance to remdesivir , and the availability of human safety data warrant testing of the efficacy of remdesivir treatment in the context of a MERS clinical trial. Our results, together with replication inhibition by remdesivir of a wide range of coronaviruses in vitro and in vivo, may further indicate utility of remdesivir against the novel coronavirus 2019-nCoV emerging from Wuhan, China.”

The monkeys who took part in the experiment were euthanized shortly after the study was completed.

By John Vibes | Creative Commons | TheMindUnleashed.com

Animals

Police Rescue Dogs Trapped In Car on Sizzling Hot Day, Owners Complain About Broken Window

Elias Marat

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Police in the UK acted quickly to save a two dogs locked inside a car in sizzling hot temperatures by smashing open a window, upsetting the car’s owner over the damage.

Officers responded Sunday to reports that a beagle and another dog were trapped in a car parked in the seaside British city of Brighton on a day of boiling heat.

In video captured of the incident, an officer can be seen jamming his baton through a rear window before finally shattering it to free the pooches.

This prompts the car alarm to go off as the car’s owners can be seen rushing toward it, upset over the police intervention.

A woman, standing with her shocked family, says: “You broke my window out!”

One of the officer responded: “It’s a hot day. You shouldn’t be leaving the dog in the car in this weather.”

The incident happened on a day when people across the region flock to the seaside resort city to dip into the beaches amid surging hot temperatures.

The onlooker who filmed the incident noted that the owners seemed unaware of the dangers posed to their pets by weather conditions.

“Where they had parked there is just no shade,” they told The Sun. “It’s directly on the seafront in 25°C (77°F) weather outside – I’ve got no idea what it was inside the car.”

The family was indignant over what they claim was an overreaction by the police.

“At first it was ‘what the f*** are you doing, why did you break my car window? I was only gone for 10 minutes,’” another witness explained.

“The bloke obviously thought he was completely in the right,” they added. “He didn’t really seem to have much empathy.”

According to UK animal welfare group RSPCA, outside temperatures of 22°C (71°F) can reach a brutal 47°C (116.6°F) inside a car within an hour.

“Police officers attended and tried to get a contact number for the owners of the car but were unable,” a Sussex Police spokesperson said. “Officers had no choice but to smash the side window to gain access and a kind member of the public donated a bottle of water.”

Authorities added that the officers let the pet owners off with a stern warning, without ticketing the family or separating their dogs from them.

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Golden Retriever Filmed Giving Woodchuck Ride Across Massachusetts Lake

Elias Marat

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There are some occasions when the natural world resembles something we might think belongs to the realm of Disney films but no – it’s simply the animal kingdom in motion.

Such was the case when a dog owner captured amazing footage of her dog giving a ride to a small rodent across a lake in Massachusetts.

Lauren Russel was with her dog, Wally the golden retriever, at Hickory Hills Lake in Lunenburg last month when the dog encountered a woodchuck in the water.

So Wally did one any good dog of his breed would do – he gave his new friend a ride back to shore.

“He was about 100 meters out and a woodchuck, I think, just crawled right up on his back and he swam back to shore with him,” Russell told WCVB on Monday.

She always knew that her Wally was a friendly pooch, but she never imagined something like this.

“We were flabbergasted. It was unbelievable. We couldn’t believe what we were seeing,” Russell continued.

To top things off, once they arrived onshore, Wally and his fast friend gave each other what appeared to be a kiss.

“They like touched snouts and then he ran away,” Russell said.

You can watch the video of the touching event here:

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Tiny Creature Frozen for 24,000 Years is Brought Back to Life

Elias Marat

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A microscopic creature has come back to life and reproduced asexually after 24,000 years of lying dormant in the permafrost of Siberia.

Russian scientists found the tiny freshwater creature, called the bdelloid rotifer, in the rich soil of the Alazeya river of Russia’s far northern Siberan region of Yakutia.

The multicellular organism is common throughout the world and is known to be extremely resilient, capable of surviving extreme cold, dryness, starvation and low oxygen.

While previous research found that it could survive a decade when frozen at -20 degrees Celsius (-4 Fahrenheit), the new study published by the journal Current Biology offers a stunning testimony of the survivability of the tiny animal – which is by far the longest survival period known of any creature in the world.

“Our report is the hardest proof as of today that multicellular animals could withstand tens of thousands of years in cryptobiosis, the state of almost completely arrested metabolism,” said Stas Malavin, an author of the study, in a statement.

Malavin’s Soil Cryology Lab in Pushchino, Russia, used a drilling rig to extract the miniscule organism from roughly a dozen feet below the remote Arctic location.

Once the ancient organism thawed, it reproduced on its own through a process of parthenogenesis. Researchers then found that it could withstand repeatedly being frozen and thawed dozens of times due to its innate processes of cell and organ protection.

“The takeaway is that a multicellular organism can be frozen and stored as such for thousands of years and then return back to life – a dream of many fiction writers,” Malavin said.

“Of course, the more complex the organism, the trickier it is to preserve it alive frozen and, for mammals, it’s not currently possible,” the scientist added. “Yet, moving from a single-celled organism to an organism with a gut and brain, though microscopic, is a big step forward.”

Researchers hope that the knowledge gleaned from studying the microscopic organism will bring further insights on how to preserve animals’ cells, tissues and organs – including those belonging to human beings.

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