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Cannabis Shops Deemed “Essential” and Allowed to Stay Open Under LA’s Emergency Coronavirus Order

The logic is simple.

Elias Marat

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(TMU) — While millions of Californians are hunkering down following successive local emergency orders followed on Thursday evening by a statewide “stay at home” order from California Governor Newsom—the priorities faced by the state remain in the hearts and minds of residents and authorities.

As the coronavirus outbreak spreads across the Golden State, authorities in Los Angeles County and the cities within its borders are taking pains to ensure that essential services continue to operate uninterrupted—including cannabis dispensaries.

The Los Angeles Times reports that despite the order to shutter all indoor malls, shopping centers, playgrounds, and nonessential retail businesses, cannabis dispensaries must continue to operate alongside hardware stores, grocery stores, and city and county government services. Like other spaces, the dispensaries must observe social-distancing guidelines and not gather over 10 people.

For a state that spearheaded the drive to legalize marijuana—first as medicine, then as a recreational substance—the logic is simple. According to the City of Los Angeles’ coronavirus FAQ, essential healthcare services include “cannabis dispensaries, or any related and/or ancillary healthcare services.”

On Thursday, Los Angeles Mayor Eric Garcetti issued the “Safer at Home” emergency order that commands all residents to stay inside their residences, limiting all movements outside of their homes unless they are engaged in certain essential activities. The order is legally enforceable, meaning that violation could bring criminal penalties including a fine or imprisonment.

But amid the siege-like conditions suffered by Californians, residents remain adamant about stocking up on not just hand sanitizers, toilet paper, and guns, but also their cannabis.

In an informal survey of cannabis dispensaries and delivery services, the Times found that dispensary-to-consumer deliveries have shot up significantly in the month of March as the gravity of the crisis surrounding the novel virus has sunken in among residents.

The Times detailed:

“When it comes to what, specifically, customers are buying, the dispensaries we checked in with report that flower (a.k.a. the dried buds of the marijuana plant) remains the top-selling category but that there has been a noticeable rise in the edibles category (THC-infused gummies, chocolates and the like). Sweet Flower and Airfield Supply Company both point to Kiva Confections’ Midnight Blueberry Camino gummies with 5 mg THC and 1 mg of CBN per piece (CBN is a cannabinoid associated with inducing a restful night’s sleep) as being particularly popular.”

On Thursday evening, Gov. Newsom issued an unprecedented order that requires nearly 40 million residents of California to stay at home for an indefinite amount of time as the state copes with rising coronavirus infection numbers and grim forecasts about potential outbreak scenarios. The order came only an hour after officials in L.A. county issued a similar mandate, and days after Bay Area counties gave similar orders.

As of Thursday night, 958 people have tested positive for the CoViD-19 novel virus while 19 people have died so far.

During his address, Newsom said:

“This is a moment we need to make tough decisions … This is a moment where we need some straight talk and we need to tell people the truth: We need to bend the curve in the state of California.”

By Elias Marat | Creative Commons | TheMindUnleashed.com

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Humans May Have Found a Way To Not Only Stop Aging – But To Reverse It as Well

Elias Marat

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Humans have long to reverse the effects of aging and prolong their lives. Whether this was due to a love of power, a love of wealth or simple human anxiety about the loss of youth, tales about immortality can be found in the folk tales of countless cultures.

And while aging is a wholly natural process, humans have always struggled to fight against it – be it through science and medicine or through the search for supposed cures such as the mythical Fountain of Youth.

And now, Israeli scientists have claimed to have figured out a solution not only to the process of biological aging – but to reverse it as well, simply by administering pure oxygen in a pressurized chamber.

In a study published Nov. 18 in the peer-reviewed journal Aging, the scientists claim to have showed how aging could be reversed in two key biological clocks in humans related to aging and illness by administering high-pressure oxygen in a pressurized chamber.

When humans grow olders and their cells divide, the sequences of DNA at the end of chromosomes – known as telomeres – grow shorter with time. After the telomeres become too short, the cell is unable to replicate and eventually dies.

While telomere shortening can keep rogue cancerous cells from multiplying rapidly, this also results in genetic aging. As a result, geriatric cells that aren’t able to divide –  also known as senescent cells – accumulate throughout our lives, and are one of the key causes of aging.

In the clinical study, 35 people aged 64 or older were given hyperbaric oxygen treatments (HBOT) for 90 minutes a day, five times a week over the course of three months. Blood samples were collected from subjects prior to the treatment, after after the first and second months of the trial, and two weeks after the trial ended.

The patients didn’t have any lifestyle, diet, or medication changes during the study. However, their blood revealed major increases in the telomere length of their cells and a decrease in the number of their senescent cells.

For the researchers, the results of the study offered proof that the process of aging is reversible.

“Researchers around the world are trying to develop pharmacological and environmental interventions that enable telomere elongation,” Prof. Shai Efrati of Tel Aviv University told the Jerusalem Post. “Our HBOT protocol was able to achieve this, proving that the aging process can in fact be reversed at the basic cellular-molecular level.”

The groundbreak study, he added, “gives hope and opens the door for a lot of young scientists to target aging as a reversible disease.”

The oxygen treatment also improved subjects’ attention, ability to process information, as well as subjects’ executive functions, the researchers said.

While attempts to halt aging through modifying one’s lifestyle or intensively exercising can provide “some inhibiting effect on telomere shortening”, the hyperbaric oxygen treatment is more effective, said Efrati’s partner at the Shamir Medical Center, Chief Medical Research Officer Amir Hadanny.

“In our study, only three months of HBOT were able to elongate telomeres at rates far beyond any currently available interventions or lifestyle modifications,” Hadanny said.

The study could open the door to a radical new approach to medical problems and medicine in general.

“Today telomere shortening is considered the ‘Holy Grail’ of the biology of aging,” Prof. Shai Efrati of Tel Aviv University told the Jerusalem Post. “We are not [just] slowing the decline – we are going backwards in time.”

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‘We Are Going To Have Famines of Biblical Proportions in 2021,’ UN Food Agency Warns

Elias Marat

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The head of the United Nations World Food Program (WFP) has delivered a stark message to the world: huge populations across the globe are facing severe “famines of biblical proportions” in the near future due to the coronavirus pandemic.

WFP head David Beasley has warned for the past several months that due to the novel coronavirus pandemic and accompanying lockdowns, nations in the developing world are faced with devastating famine and mass starvation unless action is finally taken.

However, with countries in the developed Global North facing their own budget crises and sharp economic downturns due to the ongoing health emergency, funding for the WFP that was previously available to help alleviate hunger and avert global famine won’t be available in 2021.

Speaking to The Associated Press, Beasley noted that his agency’s staffers regularly risk their lives feeding millions of hungry people in refugee camps, conflict zones, and the sites of natural disasters, but the current global crisis makes it important for him  to send “a message to the world that it’s getting worse out there … (and) that our hardest work is yet to come.”

In April, Beasley delivered a similarly urgent message to the U.N. Security Council, where he remarked that despite the breakout of the coronavirus pandemic, the world also stood  “on the brink of a hunger pandemic” that could see “multiple famines of biblical proportions” within months if critical action wasn’t taken.

And with the Nobel Peace Prize for 2020 being awarded to the World Food Program last month for its vital work providing alleviating mass hunger and boosting food security in conflict zones, Beasley has been struggling to use the win to break through the news cycle and remind people of “the travesty that we’re facing around the world.”

“We were able to avert [famine] in 2020,” Beasley said, adding that the WFP needs further funding or “we are going to have famines of biblical proportions in 2021.” 

The agency is currently hoping that it can get an additional $15 billion for the next year to deal with the growing scope of the crisis.

“If I could get that coupled with our normal money, then we avert famine around the world,” he said. 

World leaders must be prepared for the looming disaster as well as the critical role the WFP plays. As the organization says: “Until the day we have a medical vaccine, food is the best vaccine against chaos.”

In April, Beasley warned that about 135 million people faced “crisis levels of hunger or worse” in 2020 and that the number could rise by 130 million may be pushed to the brink of starvation by next year. However, on Wednesday he told AP that the number of people facing severe, crisis-level hunger had already risen to 270 million.

He added that three dozen countries could experience critical levels of hunger or famine if the WFP isn’t given the funding it requires.

According to a joint analysis by WFP and the U.N. Food and Agriculture Organization, these countries include Afghanistan, Burkina Faso, Cameroon, Central African Republic, Congo, Ethiopia, Haiti, Lebanon, Mali, Mozambique, Niger, Nigeria, Sierra Leone, Somali, South Sudan, Sudan, Syria, Venezuela, Zimbabwe, and Yemen.

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Researchers: Microbots Will Soon Enter Human Colons to Deliver Medical Payloads

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Calling it “rough terrain,” a team of researchers at Purdue University is exploring the insides of a living colon like never before, using microscopic robots the width of a few follicles of hair. Perhaps most incredibly, the anal bots require no batteries and are powered via an external electromagnetic field.

Scientists have long believed the use of microbots (and perhaps someday even nanotechnology) inside the human body could bring about a revolution in medical diagnostic abilities and drug delivery. Mechanical engineers at Purdue believe they have passed a critical first test in this journey by creating tiny robots that are controlled remotely and can efficiently deliver a payload without inflaming any tissue reactions in the notoriously sensitive colonic region.

Biomeedical engineer Luis Solorio described one of the challenges the team faced:

“Moving a robot around the colon is like using the people-walker at an airport to get to a terminal faster. Not only is the floor moving, but also the people around you. In the colon, you have all these fluids and materials that are following along the path, but the robot is moving in the opposite direction. It’s just not an easy voyage.”

Mechanical engineer David Cappelleri, also from Purdue, says the tiny robot is controlled magnetically while being monitored through ultrasound imaging.

“When we apply a rotating external magnetic field to these robots, they rotate just like a car tire would to go over rough terrain. The magnetic field also safely penetrates different types of mediums, which is important for using these robots in the human body.”

So far, the team has experimented only on live anesthetized mice and pig colons. Scaling up could be a challenge, says associate professor Craig Goergen, who points out that while the colon is a good entry point for this type of microscopic robotic research, the terrain can present some tough sledding.

“Moving up to large animals or humans may require dozens of robots, but that also means you can target multiple sites with multiple drug payloads.”

As outlined in the team’s paper, which was published in Micromachines, tests on payload delivery involved the microbots being marked with fluorescein dye in a saline vial; they imitated drug delivery mechanisms by steadily dispatching the dye over a period of time. These tests were conducted outside of the mice and pig colons.

The researchers say the tiny robots are expelled from the body via regular waste elimination. While the research is promising, scientists say coordinating multiple microbots for use inside a human body is still years off. However, the implications for such a procedure are huge.

“From a diagnostic perspective, these microrobots might prevent the need for minimally invasive colonoscopies by helping to collect tissue,” adds Goergen. “Or they could deliver payloads without having to do the prep work that’s needed for traditional colonoscopies.”

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