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Humans May Have Found a Way To Not Only Stop Aging – But To Reverse It as Well

“We are not [just] slowing the decline – we are going backwards in time,” an Israeli scientist said of the groundbreaking new study.

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Humans have long to reverse the effects of aging and prolong their lives. Whether this was due to a love of power, a love of wealth or simple human anxiety about the loss of youth, tales about immortality can be found in the folk tales of countless cultures.

And while aging is a wholly natural process, humans have always struggled to fight against it – be it through science and medicine or through the search for supposed cures such as the mythical Fountain of Youth.

And now, Israeli scientists have claimed to have figured out a solution not only to the process of biological aging – but to reverse it as well, simply by administering pure oxygen in a pressurized chamber.

In a study published Nov. 18 in the peer-reviewed journal Aging, the scientists claim to have showed how aging could be reversed in two key biological clocks in humans related to aging and illness by administering high-pressure oxygen in a pressurized chamber.

When humans grow olders and their cells divide, the sequences of DNA at the end of chromosomes – known as telomeres – grow shorter with time. After the telomeres become too short, the cell is unable to replicate and eventually dies.

While telomere shortening can keep rogue cancerous cells from multiplying rapidly, this also results in genetic aging. As a result, geriatric cells that aren’t able to divide –  also known as senescent cells – accumulate throughout our lives, and are one of the key causes of aging.

In the clinical study, 35 people aged 64 or older were given hyperbaric oxygen treatments (HBOT) for 90 minutes a day, five times a week over the course of three months. Blood samples were collected from subjects prior to the treatment, after after the first and second months of the trial, and two weeks after the trial ended.

The patients didn’t have any lifestyle, diet, or medication changes during the study. However, their blood revealed major increases in the telomere length of their cells and a decrease in the number of their senescent cells.

For the researchers, the results of the study offered proof that the process of aging is reversible.

“Researchers around the world are trying to develop pharmacological and environmental interventions that enable telomere elongation,” Prof. Shai Efrati of Tel Aviv University told the Jerusalem Post. “Our HBOT protocol was able to achieve this, proving that the aging process can in fact be reversed at the basic cellular-molecular level.”

The groundbreak study, he added, “gives hope and opens the door for a lot of young scientists to target aging as a reversible disease.”

The oxygen treatment also improved subjects’ attention, ability to process information, as well as subjects’ executive functions, the researchers said.

While attempts to halt aging through modifying one’s lifestyle or intensively exercising can provide “some inhibiting effect on telomere shortening”, the hyperbaric oxygen treatment is more effective, said Efrati’s partner at the Shamir Medical Center, Chief Medical Research Officer Amir Hadanny.

“In our study, only three months of HBOT were able to elongate telomeres at rates far beyond any currently available interventions or lifestyle modifications,” Hadanny said.

The study could open the door to a radical new approach to medical problems and medicine in general.

“Today telomere shortening is considered the ‘Holy Grail’ of the biology of aging,” Prof. Shai Efrati of Tel Aviv University told the Jerusalem Post. “We are not [just] slowing the decline – we are going backwards in time.”

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Health

Biden to Ban Menthol Cigarettes, Citing Health Impact on Youth and Black People

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The Biden administration is reportedly planning to propose an immediate ban on menthol cigarettes, a product that has long been targeted by anti-smoking advocates and critics who claim that the tobacco industry has aggressively marketed to Black people in the U.S.

On Wednesday, the Washington Post reported that the administration could announce a ban on menthol and other flavored cigarettes as soon as this week.

Roughly 85 percent of Black smokers use such menthol brands as Newport and Kool, according to the Food and Drug Administration. Research has also found that menthol cigarettes are easier to become addicted to and harder to quit than unflavored tobacco products, along with other small cigars popular with young people and African Americans.

Civil rights advocates claim that the decision should be greeted by Black communities and people of color who have been marketed to by what they describe as the predatory tobacco industry.

Black smokers generally smoke far less than white smokers, but suffer a disproportionate amount of deaths due to tobacco-linked diseases like heart attack, stroke, and other causes.

Anti-smoking advocates like Matthew L. Myers, president of Campaign for Tobacco-Free Kids, also greeted the move to cut out products that appeal to children and young adults.

“Menthol cigarettes are the No. 1 cause of youth smoking in the United States,” he said. “Eliminating menthol cigarettes and flavored cigars used by so many kids will do more in the long run to reduce tobacco-related disease than any action the federal government has ever taken.”

However, groups including the American Civil Liberties Group (ACLU) has opposed the move, citing the likelihood that such an action could lead to criminal penalties arising from the enforcement of a ban hitting communities of color hardest.

In a letter to administration officials, the ACLU and other groups including the Drug Policy Alliance said that while the ban is “no doubt well-intentioned” it would also have “serious racial justice implications.”

“Such a ban will trigger criminal penalties, which will disproportionately impact people of color, as well as prioritize criminalization over public health and harm reduction,” the letter explained. “A ban will also lead to unconstitutional policing and other negative interactions with local law enforcement.”

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Pollution Is Making Human Penises Shrink and Causing a Collapse of Fertility, Scientists Say

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With many still scoffing at the idea of rampant pollution posing a threat to humanity, a new study could drastically change the conversation: the chemicals across our environment could be the cause of shrinking human penises.

According to a new book by Dr. Shanna H. Swan, conditions in the modern world are quickly altering the reproductive development of humans and posing a threat to our future as a species.

The argument is laid out in her new book Count Down: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race.

The book discusses how pollution is not only leading to skyrocketing erectile dysfunction rates and fertility decline, but also an expansion in the number of babies born with small penises.

While it may seem like good fodder for jokes, the research could portend a grim future for humanity’s ability to survive.

Swan co-authored a study in 2017 that found sperm counts had precipitously fallen in Western countries by 59 percent between 1973 and 2011. In her latest book, Swan blames chemicals for this crisis in the making.

“Chemicals in our environment and unhealthy lifestyle practices in our modern world are disrupting our hormonal balance, causing various degrees of reproductive havoc,” she wrote in the new book.

“In some parts of the world, the average twentysomething woman today is less fertile than her grandmother was at 35,” she also wrote, noting that men could have only half the sperm count of their grandfathers.

Swan blames the disruption on phthalates, the chemicals used in plastic manufacturing that also have an impact on how the crucial hormone endocrine is produced

However, experts note that the proper implementation of pollution reduction measures could help humanity prevent the collapse of human fertility.

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Health

Visualizing The World’s Deadliest Pandemics By Population Impact

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Humanity has been battling against disease for centuries.

And while most contagious outbreaks have never reached full-blown pandemic status, Visual Capitalist’s Carmen Ang notes that there have been several times throughout history when a disease has caused mass devastation.

Here’s a look at the world’s deadliest pandemics to date, viewed from the lens of the impact they had on the global population at the time.

Editor’s note: The above graphic was created in response to a popular request from users after viewing our popular history of pandemics infographic initially released a year ago.

Death Toll, by Percent of Population

In the mid-1300s, a plague known as the Black Death claimed the lives of roughly 200 million people – more than 50% of the global population at that time.

Here’s how the death toll by population stacks up for other significant pandemics, including COVID-19 so far.

The specific cause of the Black Death is still up for debate. Many experts claim the 14th-century pandemic was caused by a bubonic plague, meaning there was no human-to-human transmission, while others argue it was possibly pneumonic.

Interestingly, the plague still exists today – however, it’s significantly less deadly, thanks to modern antibiotics.

History Repeats, But at Least We Keep Learning

While we clearly haven’t eradicated infection diseases from our lives entirely, we’ve at least come a long way in our understanding of what causes illness in the first place.

In ancient times, people believed gods and spirits caused diseases and widespread destruction. But by the 19th century, a scientist named Louis Pasteur (based on findings by Robert Koch) discovered germ theory – the idea that small organisms caused disease.

What will we discover next, and how will it impact our response to disease in the future?

Like this? Check out the full-length article The History of Pandemics

Republished from ZH with permission.

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