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Lab Grown Chicken Nuggets are Here: Google, Bill Gates and Cultured Meat

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A San Francisco Bay Area food technology company called Memphis Meats recently finished their lab grown chicken. They fried it into chicken strips and fed it to people at an event. It was produced from stem cells programmed to reproduce animal tissue.

It could be considered the second recent node of progress when it comes to “cultured” lab grown meat, after a lab produced hamburger was tested a few years ago. The concept of cultured meat goes back several decades.

A headline from Gizmodo cheered it on saying “Lucky Humans Just Ate the Very First Lab-Grown Chicken Tenders.”

According to an article titled “Lab-grown chicken strips, made from animal cells, debuted by startup”:

“The company estimates it costs under $9,000 to make one pound of the meat, the Journal reported. Memphis Meats expects price should come down in the next several years and let them offer their products publicly in 2021, according to Business Insider.”

This is a picture of it.

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(Image credit: Eater)

According to Eater:

“Back in 2015, the San Francisco Bay Area-based company crowdfunded its mission to grow “clean meat.” Since then, it’s introduced a lab-grown meatball and plans to grow Thanksgiving turkey in a lab. The company has raised a total of $3 million, and plans to continue conversations with investors in the coming months. If all goes according to plan, Memphis Meats’ lab-grown poultry and beef will be available in supermarkets by 2021.

Both Memphis Meats and Mosa Meat — which is based in the Netherlands and counts Google co-founder Sergey Brin among its investors — have produced lab-grown burger-like meat patties from bovine cells. Memphis says they are the first to grow poultry cells in a lab.”

Upon investigating who holds stock in cultured meat, all trails go back to Silicon Valley.

Google co-founder and president of its parent company Alphabet, Sergey Brin funded the creation of the first cultured beef patty, put together in a petri dish. It looks like a patty made of thin strands of ground beef, because the thin strands of cow muscle were artificially exercised by stretching them.

meat

(Image credit: Daily Mail)

According to a person who ate it:

“I was one of the two people to taste the so-called Frankenburger: the world’s first lab-grown beef burger, a five-ounce patty grown from cow stem cells that took a Dutch scientist four years of research and $332,000 to create.

My biggest complaint was that that even fried in oil and butter, by a Gordon Ramsay-trained chef, the cultured beef burger tasted about as dry as a turkey burger. The first cultured beef burger had 20,000 muscle fibers but zero fat cells.”

Bill Gates has praised a similiar corporation called Hampton Creek Foods, which is connected to the founder of Memphis Meats. Uma Valeti is the CEO and co-founder of Memphis Meats, the start up that produced the lab cultured chicken nuggets.

Valeti also sits in an advisory position with the Good Food Institute, one out of 25 people who include Hampton Creek Foods founder Josh Balk.

Josh Balk is a player in biotechnology, and was Senior Director of Food Policy for The Humane Society.

According to Wikipedia: “In 2011, Balk founded Hampton Creek Foods with Joshua Tetrick. Bill Gates named Hampton Creek one of three companies that will forever change the food system.”

But it turns out Google is involved with Hampton Creek Foods.. Which puts them not far from the effort to make lab cultured chicken. According to Wikipedia:

“Hampton Creek hired Dan Zigmond, described by TechCrunch as “Google’s main data guy,” in June 2014 to build a database for the company’s research into plants. Zigmond, who had been working for eight years on YouTube and Google maps, stated his plan was to “build the world’s largest plant database.” Hampton Creek signed chef Ben Roche in July 2014.”

So Google, Bill Gates, and other players in Silicon Valley are investing in biotechnology: but who are they tied to?

Google is deeply tied to the US military industrial complex, and was created in the bowels of the academic, institutional root of the intelligence agencies in the US.

Google is rooted in Harvard where it was co-founded by Sergey Brin.

Reading from an extensive article by Nafeez Ahmed titled “How the CIA made Google: Inside the secret network behind mass surveillance, endless war, and Skynet”:

“In 1994 — the same year the Highlands Forum was founded under the stewardship of the Office of the Secretary of Defense, the ONA, and DARPA — two young PhD students at Stanford University, Sergey Brin and Larry Page, made their breakthrough on the first automated web crawling and page ranking application. That application remains the core component of what eventually became Google’s search service. Brin and Page had performed their work with funding from the Digital Library Initiative (DLI), a multi-agency programme of the National Science Foundation (NSF), NASA and DARPA.

But that’s just one side of the story.

Throughout the development of the search engine, Sergey Brin reported regularly and directly to two people who were not Stanford faculty at all: Dr. Bhavani Thuraisingham and Dr. Rick Steinheiser. Both were representatives of a sensitive US intelligence community research programme on information security and data-mining.”

Stanford and MIT (Massachusetts Institute of Technology) are among institutions that birth the individuals who compose the alphabet agencies of the US government: people from these colleges end up in agencies from the NSA to the DOD. Reading from an article we published titled “The Institutes of Technology Exposed: Academia’s Surprising Role in War, Science, and the System”:

“Entire books have been written about this institution’s involvement in warfare, such as the 1993 book “The Cold War and American Science: The Military-Industrial-Academic Complex at MIT and Stanford.” From World War II, to the Cold War, to the present day, MIT has been and continues to be a central hub of science for the power structure.

Governments and corporations use money to influence science toward a certain trajectory, giving grants and recruiting people.”

To examine this axis of power between academic institutions, corporations, and the state, let’s take a look at an institution as influential to the 20th Century as Harvard: Massachusetts Institute of Technology.

MIT is also enthusiastically supporting cultured meat. They have a long history. MIT staff participated in the nuclear bomb’s creation, and then geoengineering, which was dubbed the “New Manhattan Project.”

A professor of physics at MIT named Philip Morrison personally helped kill thousands of people with the nuclear bombing of Hiroshima and Nagasaki, Japan in 1945.

According to Wikipedia: “As leader of Project Alberta‘s pit crew he helped load the atomic bombs on board the aircraft that participated in the atomic bombing of Hiroshima and Nagasaki. After the war ended, he traveled to Hiroshima as part of the Manhattan Project’s mission to assess the damage.”

MIT researchers fed children radiation via cereal, children who were declared “feeble-minded” in a eugenics influenced 1940’s culture of academia.

According to PO:

“In the late 1940s, Boyce was one of some 90 children, most of whom were classified as “feeble-minded,” selected by MIT to be used as test subjects. With offers of free meals and Boston Red Sox tickets, they’d been coaxed to join a “Science Club” without knowing that their inclusion would make them guinea pigs for various radiation-laden nutrition studies funded by Quaker Oats.

It wasn’t until decades later, on that winter morning in 1994, that Boyce became aware of what he’d been secretly put through. It incited one of history’s most searing debates about the ethics of academic research and the necessity of informed consent.”

MIT was working with Quaker Oats. Experimental food, dangerous biotechnology: many of these things originate in institutions such as MIT or Stanford.

Academic institutions, processed food corporations using biotechnology, Pentagon affiliated technology barons,  this is the full picture: a piece of a powerstructure that affects us every day.

It’s difficult to say in one article how this power operates, and how that will influence our future: but this can be a starting point to your own research. Type everything into your non-Google search engine and research away.

(Image credit: Eater, Cloudinary, Philanthropy)

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Company allegedly asks employees if they are stressed, and then fires the ones who said yes; leaked letter goes viral

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In an unsettling development that’s stirring debates across the corporate sector, a leaked letter has revealed that a well-known company allegedly dismissed several employees based solely on their self-reported stress levels. YesMadam, a startup known for its innovative approach in the beauty industry, is now at the center of a controversy that questions the ethics of its management practices. This incident raises profound concerns about the treatment of mental health in the workplace and the methods companies employ to maintain a productive work environment. As the story unfolds, one can’t help but wonder: Is the path to a stress-free workplace paved with such drastic measures? What exactly did the leaked letter say, and how has the public reacted?

Details of the Incident

The controversy surrounding YesMadam began when a screenshot of an email from the company’s HR department surfaced online. This email stated that the company had conducted a survey to understand the stress levels of its employees and had made the “difficult decision” to terminate those who reported significant stress. The decision was described as immediate, and the affected employees were informed they would receive further details separately​

The leaked email and the company’s response highlight a disconnect between the company’s public relations statements and the perceptions of its employees and the public. The incident has ignited a broader discussion about the pressures faced by employees in high-stress jobs and the responsibilities of employers to address mental health proactively rather than reactively​

This incident comes at a time when workplace stress is a growing concern in India, with reports suggesting that about 62% of Indian employees experience burnout, a figure significantly higher than the global average​

The World Health Organization also notes that work-related anxiety and depression contribute to substantial economic losses globally due to lost productivity​.

Company’s Response

Image Credits: Twitter @pitdesi

In the wake of the viral backlash from the leaked email concerning the termination of employees who reported high stress levels, YesMadam swiftly issued a response denying any actual firings related to the survey results. The company clarified that the implicated social media posts and the controversial email were elements of a deliberate campaign aimed at promoting awareness about mental health issues within the workplace. YesMadam emphasized that rather than dismissing employees, it had offered them a chance to reset and recharge, incorporating breaks and supportive measures like the “Happy 2 Heal” program and a new “De-Stress Leave Policy,” which provides six days of paid leave specifically for mental health recovery​

This initiative includes complimentary spa sessions at home, aiming to underscore the company’s commitment to fostering a workplace environment supportive of mental health. Despite these clarifications, the execution of their campaign was widely criticized for its insensitivity, prompting debates about the authenticity and effectiveness of such public relations strategies in addressing serious workplace issues. The backlash continued as the public and employees expressed mixed reactions to the company’s attempts at damage control and its methods of addressing mental health proactively​

Expert Opinions on Workplace Mental Health Initiatives

Experts across various fields stress the importance of addressing specific mental health diagnoses within the workplace by providing tailored support and resources. This can significantly enhance the overall well-being of employees and, by extension, the productivity of the organization. Here’s a synthesis of the key recommendations from mental health professionals:

Tailored Support for Specific Conditions: Experts suggest that workplaces should offer targeted resources to address common conditions like anxiety, depression, and ADHD. This could include stress management workshops, mental health apps, flexible work arrangements, and mental health training for managers​.

Economic Benefits of Mental Health Investments: There is a strong business case for investing in mental health. Research indicates that for every dollar spent on treating common mental disorders, there is a return of four dollars in improved health and productivity​.

Challenges of Implementation: Creating a supportive environment for mental health is complex and requires a proactive approach from leadership. Resistance to change and budget constraints are common challenges. However, the benefits in terms of reduced absenteeism and higher employee engagement are substantial​.

Building a Supportive Culture: A mentally healthy workplace culture is underpinned by transparent communication and fair people management. Employers that create an environment of psychological safety, where employees feel they can express themselves and seek help without fear, see better overall work health outcomes​.

Importance of Employer Involvement: Mental health professionals emphasize that employer involvement is crucial. Effective mental health support in the workplace includes providing flexible schedules, onsite mental health staff, and health promotion programs. Surveys indicate that while many employees appreciate these efforts, there is room for improvement in how these programs are communicated and implemented​.

Impact Of Company Culture On Employee Mental Health

The YesMadam controversy underscores a critical concern in modern workplaces: the impact of company culture on employee mental health and the broader implications for the business environment. Companies are increasingly recognizing that fostering a mentally healthy workplace is not just an ethical obligation but also a strategic asset.

A supportive company culture that aligns with employees’ values significantly enhances their mental well-being. Such environments encourage open communication, where employees feel safe to express concerns and seek help without fear of retribution. This kind of supportive culture not only helps in retaining talent but also attracts new talent looking for empathetic workplaces​

From an economic perspective, investing in mental health support can yield substantial returns. According to research by the World Health Organization, every $1 invested in scaling up treatment for common mental disorders such as depression and anxiety leads to a return of $4 in improved health and productivity​

Companies that prioritize mental health enjoy increased productivity, lower absenteeism, and reduced healthcare costs.

However, establishing a mentally healthy workplace culture is not without challenges. Resistance to change and budget constraints are significant hurdles. Companies may face initial resistance when altering long-standing corporate norms that did not previously prioritize mental health. Additionally, although the return on investment for mental health initiatives is high, the initial setup requires a commitment of resources that some budget-conscious leaders might be hesitant to approve​.

The Intersection of Mental Health and Workplace Dynamics

The YesMadam incident has not only highlighted the critical importance of addressing mental health in the workplace but also underscored the delicate balance companies must maintain in their approach. While YesMadam’s intentions to promote mental health awareness were clear, the execution through a social media campaign sparked controversy and backlash, revealing a profound disconnect between the company’s strategy and public perception. This incident serves as a potent reminder of the need for transparency, sensitivity, and genuine support in corporate mental health initiatives.

Businesses stand at a pivotal juncture where investing in mental health not only supports their workforce but also enhances their operational efficacy, reflecting in improved productivity and reduced absenteeism. Moreover, establishing a culture that promotes psychological safety and open communication can transform the workplace environment, encouraging employees to thrive both professionally and personally.

Moving forward, it is imperative for companies to learn from incidents like these. By implementing well-thought-out mental health policies that genuinely address the needs of employees, businesses can foster a supportive environment that is both resilient and adaptive to the challenges of modern work dynamics. This proactive approach in mental health care will not only benefit employees but also contribute significantly to the company’s long-term success.

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Man sees deadly brain tumour shrink by half thanks to new treatment

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Glioblastoma, an aggressive and often fatal form of brain cancer, has long posed a formidable challenge to doctors and patients alike. Yet, a groundbreaking clinical trial is offering a glimmer of hope, capturing global attention for its potential to revolutionize cancer treatment. A 62-year-old engineer, faced with a grim prognosis, has experienced something extraordinary—his tumour has shrunk significantly in a matter of weeks. This remarkable outcome marks the beginning of a journey that could redefine how we treat one of the most challenging cancers. What makes this approach so promising, and how could it change the future for patients?

Understanding Glioblastoma

Glioblastoma, often referred to as glioblastoma multiforme (GBM), is the most aggressive and common form of primary brain cancer in adults. Originating from glial cells—specifically astrocytes that support nerve cells—this malignancy is notorious for its rapid growth and diffuse infiltration into surrounding brain tissue, making complete surgical removal challenging.

Characteristics and Challenges:

  • Aggressiveness: Glioblastomas are classified as grade IV tumors, indicating a high degree of malignancy. They proliferate swiftly and have a propensity to invade adjacent brain regions, complicating treatment efforts.
  • Symptoms: Early signs are often nonspecific, including persistent headaches, personality changes, nausea, and symptoms resembling a stroke. As the tumor advances, symptoms can escalate rapidly, potentially leading to unconsciousness.
  • Prognosis: The outlook for glioblastoma patients remains dire. Even with aggressive treatment—comprising surgery, radiation, and chemotherapy—the median survival time is approximately 12 to 15 months, with a five-year survival rate of less than 10%.

Current Treatment Modalities:

  1. Surgical Intervention: The primary approach involves maximal safe resection of the tumor to alleviate symptoms and reduce mass effect. However, due to the tumor’s infiltrative nature, achieving complete removal is often unfeasible.
  2. Radiation Therapy: Post-surgical radiation aims to destroy residual cancerous cells. This treatment is typically administered over several weeks and is a cornerstone in glioblastoma management.
  3. Chemotherapy: Temozolomide is the standard chemotherapeutic agent used alongside radiotherapy. It functions by interfering with the tumor’s DNA replication, thereby inhibiting cell division.

Despite the multimodal treatment approach, glioblastomas invariably recur, underscoring the critical need for novel therapeutic strategies. The recent clinical trial at University College London Hospitals NHS Foundation Trust (UCLH) exemplifies such innovation. By delivering targeted radioactive therapy directly into the tumor, this method aims to eradicate cancer cells while preserving healthy brain tissue. Paul Read, the first participant in this trial, described it as a “lifeline,” noting, “I have got nothing to lose and everything to hope for.”

The Innovative Treatment

In a pioneering effort to combat glioblastoma, University College London Hospitals NHS Foundation Trust (UCLH) has initiated a clinical trial exploring a novel treatment approach. This method involves the direct injection of low-level radioactivity into the tumor, aiming to eradicate cancer cells while preserving healthy brain tissue.

The procedure begins with surgeons removing as much of the tumor as possible. Subsequently, a small medical device known as an Ommaya reservoir is implanted under the patient’s scalp, connected to the tumor site via a tube. This reservoir facilitates the direct administration of the radioactive drug ATT001, an iodine-123 labeled PARP inhibitor, into the tumor. The treatment is administered weekly over a period of four to six weeks. The localized delivery ensures that the radioactivity targets cancerous cells specifically, minimizing damage to surrounding healthy tissue.

Paul Read, a 62-year-old engineer from Luton, was the first patient to participate in this trial. Diagnosed with glioblastoma in December 2023, he underwent initial treatments, including surgery, radiotherapy, and chemotherapy. However, by July, his tumor had resumed growth. Upon joining the trial, Mr. Read experienced a remarkable 50% reduction in tumor size within weeks. He described the trial as a “lifeline,” stating, “I have got nothing to lose and everything to hope for.” Notably, he reported minimal side effects, aside from slight fatigue.

Dr. Paul Mulholland, the UCLH consultant medical oncologist who designed the trial, expressed optimism about the results, noting, “We’ve just gone through [Paul’s] scan results with him and his end of treatment scan shows a reduction in the tumor, which is really quite remarkable for … .” The trial, known as CITADEL-123, plans to treat up to 40 patients in its initial phase, with future plans to increase the radiation dose and combine the drug with immunotherapy to enhance the body’s immune response against cancer.

Paul Read’s Journey

Image Credit: Twitter @Independent

Paul Read’s battle with glioblastoma began when he was diagnosed with this aggressive brain tumor in December of the previous year. His journey through the standard treatment protocol of surgery, radiotherapy, and chemotherapy seemed all too familiar for glioblastoma patients, characterized by brief respites from the disease before inevitable regrowth. By July, despite the aggressive treatment, his tumor had started growing again, a common and disheartening phase for many battling this condition.

Determined to fight the disease, Paul enrolled as the first patient in a pioneering clinical trial at University College London Hospitals NHS Foundation Trust (UCLH), seeking a new kind of treatment that promised more than just temporary control. “I am more than happy – even if it doesn’t benefit me, it may benefit someone else down the line,” Paul stated, reflecting a selfless perspective on his participation.

The innovative treatment involved injecting a radioactive drug directly into his tumor, a process facilitated by the implantation of a small medical device called an Ommaya reservoir under his scalp. This device connected directly to the tumor, allowing for precise delivery of the treatment intended to minimize harm to healthy brain tissue. Remarkably, within just a few weeks of starting the trial, Paul observed a significant reduction in his tumor size, halved from its original state. “This trial was a lifeline,” he remarked, underscoring the personal significance of the experimental approach not just as a treatment but as a beacon of hope.

Paul’s response to the treatment was not just physical but also emotional, as he experienced minimal side effects, a stark contrast to the often debilitating impacts of conventional treatments. “I am feeling very good,” he noted, which highlighted the dual benefits of the trial—efficacy in treating the tumor and maintaining quality of life.

Expert Insights

The clinical trial at University College London Hospitals NHS Foundation Trust (UCLH) has not only showcased remarkable patient outcomes but also garnered significant attention from medical experts in the field. Dr. Paul Mulholland, the oncologist and chief investigator of the trial, expressed optimism about the potential of this new treatment to change the landscape of brain cancer therapy. “We have to aim to cure this disease,” he asserted, highlighting the unique opportunity provided by the localized nature of glioblastoma, which does not typically metastasize beyond the brain.

Dr. Mulholland further explained the scientific rationale behind the approach, “Primary brain tumors do not metastasize around the body and generally stay in the same location in the brain. It doesn’t spread to the rest of the body, so using a targeted – directly into the tumor – approach makes sense.” This targeted approach allows for high doses of therapeutic agents right at the site of the tumor, maximizing the impact on cancer cells while sparing healthy tissue.

The optimism is also shared by other experts in the field. Dr. Simon Newman, chief scientific officer at The Brain Tumour Charity, commented on the trial’s implications, “These tumors are notoriously difficult to treat, and research into immunotherapy has had mixed results due to the tumor’s ability to hide from the immune system. However, we are encouraged by the findings from this study as there is an urgent need for new approaches to monitor and treat this devastating disease.”

Hope for the Future

The promising results of the clinical trial at University College London Hospitals NHS Foundation Trust (UCLH) have instilled a new sense of hope among patients, families, and clinicians alike in the fight against glioblastoma. This hope is not only rooted in the current successes but also in the potential for future advancements that this research may enable.

As Dr. Paul Mulholland, the trailblazing oncologist behind the trial, explains, “The dose of radiation will be increased throughout the trial and the plan is then to combine the drug with an immunotherapy—which trains the body’s own immune system to kill cancer.” This forward-looking approach aims not only to refine the treatment but to possibly establish a new standard of care that could dramatically improve survival rates and quality of life for patients with glioblastoma.

Furthermore, the enthusiastic reception and support from the broader medical and research community highlight the importance of continued investment in innovative cancer treatments. Dr. Simon Newman, chief scientific officer at The Brain Tumour Charity, reflected on the broader implications: “Immunotherapies have shown progress in other cancer types, and we hope to see similar advancements for brain tumors. We are pleased to see progress in this area and look forward to following this work as it advances to larger clinical trials.”

This hope is not just clinical but deeply personal for those affected. As Paul Read, a participant in the trial, poignantly shares, “It will be wonderful if this treatment helps me, and if it doesn’t, it doesn’t. I am more than happy—even if it doesn’t benefit me, it may benefit someone else down the line.” His sentiment encapsulates the dual aspirations of the trial: to find a cure and to contribute to a legacy of improved outcomes for future generations. This trial, therefore, is not just about treating a disease but about changing the narrative of glioblastoma for patients worldwide.

A New Dawn in Glioblastoma Treatment

The innovative clinical trial led by University College London Hospitals NHS Foundation Trust marks a significant advancement in the treatment of glioblastoma. By successfully reducing Paul Read’s tumor by half through targeted radioactive therapy, this trial offers a beacon of hope not just for him but for all glioblastoma patients. The potential to change the standard treatment approach for this aggressive cancer could improve survival rates and quality of life for many.

As we look to the future, the integration of this therapy with immunotherapy promises even greater strides in treating not only glioblastoma but potentially other localized cancers. The ongoing research and dedication of medical professionals and researchers are vital to turning these possibilities into realities.

This trial not only signifies a breakthrough in medical treatment but also embodies the relentless pursuit of better outcomes for patients facing dire prognoses. It reinforces the importance of continuous innovation and optimism in the face of one of the toughest medical challenges.

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FDA Approves 1st New Drug for Schizophrenia in More Than 30 Years

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Imagine battling an invisible enemy that distorts your sense of reality, turning even familiar faces into strangers and thoughts into chaos. For millions living with schizophrenia, this is a daily reality—a condition that affects over 21 million people worldwide and has seen little innovation in treatment for decades. But now, for the first time in over 30 years, the FDA has approved a new drug, offering hope where stagnation once reigned.

This breakthrough doesn’t just mark a milestone in medicine—it signals a shift in how we might better address one of the most complex mental health challenges of our time. What sets this treatment apart, and how might it reshape the lives of those who’ve long waited for an answer?

The Drug: A New Approach to Schizophrenia Treatment

The recently approved drug marks a paradigm shift in schizophrenia treatment, addressing the disorder in a way that hasn’t been seen for over three decades. Traditional antipsychotics work by blocking dopamine receptors in the brain to manage symptoms like hallucinations and delusions. While effective for some, these medications often come with significant drawbacks, including severe side effects and limited efficacy for a substantial portion of patients.

What makes this new drug stand apart is its groundbreaking mechanism of action. Instead of focusing solely on dopamine, it targets other neurotransmitter pathways that are believed to play a role in schizophrenia’s complex neurological underpinnings. This innovative approach provides an alternative for individuals who have struggled with the limitations of current treatments.

“This drug takes the first new approach to schizophrenia treatment in decades,” explained Tiffany Farchione, M.D., director of the Division of Psychiatry in the FDA’s Center for Drug Evaluation and Research. “This approval offers a new alternative to the antipsychotic medications people with schizophrenia have previously been prescribed.” This advancement not only broadens the options available but also reinvigorates hope for future developments in psychiatric medicine.

Understanding Schizophrenia and Its Challenges

Schizophrenia is more than a mental health condition—it’s a life-altering disorder that affects how people perceive reality, interact with others, and navigate daily life. Characterized by symptoms like hallucinations, delusions, disorganized thinking, and emotional withdrawal, it impacts over 21 million people globally, cutting across geographical, social, and economic boundaries.

The disorder is not only debilitating for those who live with it but also challenging for their families and caregivers. Schizophrenia often leads to unemployment, social isolation, and a reduced quality of life, making it one of the leading causes of disability worldwide. “Schizophrenia is a leading cause of disability worldwide. It is a severe, chronic mental illness that is often damaging to a person’s quality of life,” explained Dr. Tiffany Farchione, emphasizing the far-reaching effects of the condition.

Current treatments, though lifesaving for many, come with significant hurdles. Antipsychotic medications, which have formed the cornerstone of schizophrenia management for decades, primarily target dopamine imbalances in the brain. However, these treatments are far from perfect, often leading to undesirable side effects such as weight gain, drowsiness, and a higher risk of metabolic disorders. Worse yet, a considerable number of patients fail to respond adequately, leaving them in desperate need of new therapeutic options.

Clinical Trials and Effectiveness

The recently approved drug, Cobenfy, represents a significant leap in schizophrenia treatment. Unlike traditional antipsychotics that primarily block dopamine receptors, Cobenfy takes an entirely novel approach by targeting the cholinergic system. It combines two active ingredients: xanomeline, a muscarinic receptor agonist, and trospium chloride, a peripherally acting muscarinic antagonist. This dual action allows it to modulate neurotransmitter pathways involved in schizophrenia while minimizing potential side effects.

The FDA’s approval of Cobenfy is backed by extensive research, including two pivotal randomized, double-blind, placebo-controlled trials. These studies demonstrated significant reductions in symptoms of schizophrenia, as measured by the Positive and Negative Syndrome Scale (PANSS) total score. Over a five-week period, participants experienced improvements in both positive symptoms (such as hallucinations and delusions) and negative symptoms (such as social withdrawal and lack of motivation) compared to a placebo.

Notably, Cobenfy’s side effect profile distinguishes it from existing antipsychotics. Commonly reported adverse effects include nausea, constipation, dizziness, and abdominal discomfort. However, it shows a lower incidence of metabolic issues and movement disorders, side effects that often discourage patients from adhering to traditional medications. Trospium chloride, one of the drug’s components, plays a critical role in mitigating side effects by preventing xanomeline from impacting peripheral muscarinic receptors.

Dr. Tiffany Farchione, director of the Division of Psychiatry in the FDA’s Center for Drug Evaluation and Research, praised the innovation behind this treatment: “This drug takes the first new approach to schizophrenia treatment in decades. This approval offers a new alternative to the antipsychotic medications people with schizophrenia have previously been prescribed.”

Cobenfy not only addresses the limitations of existing therapies but also symbolizes a new frontier in psychiatric care. Its approval marks the first antipsychotic to work through cholinergic receptors instead of dopamine receptors—a shift that could inspire further breakthroughs in mental health treatments.

The Potential Benefits and Risks

Cobenfy offers a new ray of hope for individuals living with schizophrenia, particularly for those who have struggled with the limitations of existing antipsychotic treatments. Its novel mechanism of action, targeting the cholinergic system rather than dopamine receptors, provides an alternative for patients who either do not respond well to or cannot tolerate traditional medications.

One of the most promising aspects of Cobenfy is its potential to reduce common side effects associated with older treatments. While traditional antipsychotics are often linked to metabolic issues, sedation, and movement disorders, Cobenfy has shown a comparatively milder side effect profile. Clinical trials highlighted common side effects such as nausea, constipation, and dizziness, but these were generally manageable and did not lead to significant dropout rates. Additionally, its dual composition—xanomeline and trospium chloride—ensures that peripheral side effects are minimized without compromising its efficacy in the central nervous system.

However, like any medication, Cobenfy is not without its risks. Some participants in the trials reported gastrointestinal symptoms like indigestion, abdominal pain, and diarrhea, while others experienced hypertension and tachycardia. These side effects underline the importance of careful monitoring by healthcare providers during treatment.

Expert Reactions and Patient Perspectives

The approval of Cobenfy has sparked widespread discussions among medical professionals and patient advocacy groups, many of whom see it as a transformative moment in the treatment of schizophrenia. Experts have lauded the drug’s innovative approach, emphasizing its potential to address unmet needs in the psychiatric community.

“Schizophrenia is a leading cause of disability worldwide. It is a severe, chronic mental illness that is often damaging to a person’s quality of life,” said Dr. Tiffany Farchione, director of the Division of Psychiatry in the FDA’s Center for Drug Evaluation and Research. Her statement underscores the importance of advancements like Cobenfy in improving the lives of those affected by this debilitating condition.

Patient advocacy groups have also welcomed the news, expressing optimism about the new treatment option. For many individuals living with schizophrenia, the limitations of current antipsychotic medications have long been a source of frustration. Stories from clinical trial participants highlight the potential for improved quality of life, with some noting reductions in distressing symptoms and an enhanced ability to engage in everyday activities.

At the same time, experts remain measured in their excitement, cautioning that no single treatment is a panacea. They stress the importance of continued monitoring to understand the long-term effects and real-world impact of Cobenfy. Additionally, some highlight the need for ongoing support systems, including psychotherapy and community-based resources, to complement medication and address the multifaceted challenges of schizophrenia.

For patients and their families, Cobenfy symbolizes a step forward, not just in treatment options but in the broader conversation about mental health care. It provides a new sense of hope for those who have long waited for innovation in a field that often feels stagnant.

A New Dawn in Schizophrenia Treatment

The approval of Cobenfy marks a turning point in the treatment of schizophrenia, offering a long-awaited alternative to the limited options that have dominated the field for decades. With its innovative mechanism targeting the cholinergic system and its promising safety profile, this medication brings new hope to patients and their families who have struggled with the challenges of this complex disorder.

As experts continue to study its long-term impact, Cobenfy’s approval serves as a reminder of the importance of innovation in addressing mental health conditions. It not only provides a vital new option for those living with schizophrenia but also paves the way for further research and development in psychiatric medicine.

For the millions affected by schizophrenia, this breakthrough is more than just a medical milestone—it’s a symbol of progress, resilience, and the relentless pursuit of solutions for those most in need. While challenges remain, Cobenfy’s arrival underscores a renewed commitment to improving lives and advancing mental health care.

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Kellogg’s CEO Faces Backlash for Saying People Should Eat Cereal for Dinner to Save Money

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Gary Pilnick, CEO of Kellogg, recently stirred controversy by suggesting that cereal is no longer just for breakfast. It’s also a budget-friendly dinner option. His comments have sparked a fiery debate amid soaring food prices and growing economic strain

As families grapple with the highest food-related expenses in three decades, Pilnick’s advice comes as many scrutinize every dollar spent on groceries. While this shift towards cereal for dinner is proposed as a cost-saving measure, it raises questions about nutritional adequacy and the long-term economic impacts on household budgets.

Kellogg’s CEO Suggests Cereal for Dinner 

Kellogg’s CEO Gary Pilnick faced public backlash in late February 2024 after suggesting people eat cereal for dinner to save money. “Cereal for dinner is something that is probably more on trend now, and we would expect to continue as that consumer is under pressure,” Pilnick said during an interview with CNBC on Squawk on the Street. He made this recommendation during a television interview amid rising inflation and cost of living concerns. Critics viewed the suggestion as insensitive to the food insecurity many families experience. They argued promoting cereal as a dinner substitute trivialized affording nutritious meals, especially since cereal often lacks the nutritional value of a balanced dinner. 

Pilnick’s comments coincided with Kellogg’s marketing campaign promoting “cereal for dinner,” which fueled accusations of profiting from economic hardship. The controversy highlighted the disconnect between corporate messaging and people’s financial struggles, drawing comparisons to historical examples of perceived elitism, such as “Let them eat cake.”

Kellogg launched the “Give chicken the night off” campaign which positions its cereals—from Frosted Flakes to Corn Flakes—as viable dinner alternatives. This strategy targets consumers seeking to stretch their food budgets amid escalating prices. 

Marianne Williamson criticized cereal companies advertising their product as a dinner option for hungry people. She argued on X (formerly Twitter) that this isn’t simply understanding people’s situations but taking advantage of their hunger for profit.

“Advertising to hungry people that cereal might be good for dinner is not ‘meeting people where they are,’” self-help author Marianne Williamson wrote on X, formerly Twitter.

Gary Pilnick, the company’s CEO, champions cereal as a cost-effective solution during these economically challenging times, asserting its value compared to traditional dinner choices. However, the campaign’s cheery approach was not reflected in the same way by everyone, drawing criticism for seeming to trivialize many’s financial hardships.

The Cost of Groceries and Dining Out

Household spending on groceries and dining out has surged since the pandemic began, significantly straining budgets nationwide. This surge isn’t happening in isolation; it’s part of a broader inflationary trend affecting the entire economy. Supply chain disruptions, increased energy costs, and a tight labor market have all contributed to rising prices across various sectors, with food being particularly affected. 

Data from the U.S. Department of Agriculture (USDA) reveals that in 2023, consumers allocated 11.2% of their disposable income to food—the highest percentage since 1991. This stark figure underscores the growing financial burden of feeding a household.

Looking closer at grocery aisles, we see significant price increases across key food categories. According to the Bureau of Labor Statistics (BLS) Consumer Price Index, items like meat, poultry, fish, and eggs have seen substantial price jumps in recent years. This means that staples that form the base of many family meals are becoming increasingly expensive. It’s also important to note that grocery costs aren’t uniform across the country. Regional differences in transportation costs, local agricultural production, and regional economic conditions mean that some consumers feel the pinch more acutely than others.

The cost of dining out has also skyrocketed, further compounding the financial pressure on families. Restaurants face challenges, including rising ingredient costs, higher labor costs due to wage pressures, and increased operational expenses. These costs are inevitably passed on to consumers through higher menu prices. As a result, many people are changing their dining habits. Some are cutting back on dining out altogether, while others opt for cheaper options like fast food or quick-service restaurants instead of full-service establishments. This shift in consumer behavior also impacts the restaurant industry, with some establishments struggling to maintain profitability due to decreased customer traffic.

Consumer Reactions and Public Opinion

Consumer reaction to Kellogg’s CEO Gary Pilnick’s suggestion that people eat cereal for dinner to save money was overwhelmingly negative.

Consumers viewed Pilnick’s suggestion as insensitive and out-of-touch with ordinary people’s financial struggles. They felt it trivialized food insecurity and offered a simplistic solution to a complex problem. This sentiment is reflected in articles like this one from CTV News.

Senator Peter Welch also highlighted the stark wage disparity within Kellogg’s itself. In a pointed criticism, Senator Welch noted that a Kellogg’s worker earning $20 per hour would need to work for 96 years to match CEO Pilnick’s annual compensation of $4 million. The Senator argued that the real issue wasn’t about Americans needing to resort to cereal for dinner but rather about corporate practices and executive compensation contributing to economic inequality.

Social media responses further captured the public’s frustration. An X user tweeted a sardonic comment: “I wonder what cereal he and his family are eating for dinner.” This pointed remark underscored the perceived hypocrisy of a wealthy executive suggesting budget-conscious meal options while likely not following such advice himself.

Can Cereal Really Replace Dinner?

Kellogg’s CEO Gary Pilnick promoted cereal as a budget-friendly dinner option. However, it is essential to determine whether this shift meets nutritional needs, which requires comparing cereals to traditional meals. 

According to Katherine Shary, a registered dietitian at Children’s Healthcare of Atlanta, “There is no rule that says you can’t have cereal for dinner. But you must follow certain guidelines to find the healthiest cereal and make it a filling, healthy meal.” 

Different cereals provide varying nutrients. Here’s a breakdown of typical cereals:

  • Carbohydrates and Sugars: Most cereals contain high carbohydrates, offering quick energy. However, many varieties, especially those aimed at children, include added sugars. For instance, Frosted Flakes have up to 12 grams of sugar per serving, leading to energy spikes and crashes.
  • Protein Content: Traditional dinners often feature significant protein sources like meat, beans, or tofu. In contrast, cereals usually provide only 2-4 grams of protein per serving. This low protein content may reduce satiety, causing hunger shortly after eating.
  • Fiber and Whole Grains: Whole grain cereals supply good fiber, supporting digestive health and prolonged fullness. Not all cereals use whole grains, and some lack sufficient fiber compared to meals that include vegetables and legumes.
  • Vitamins and Minerals: Many cereals are fortified with vitamins and minerals such as iron, B vitamins, and vitamin D. While fortification helps prevent certain deficiencies, it may not match the comprehensive nutrient profile of a varied dinner that includes fruits, vegetables, and proteins.

Comparing Cereal to Traditional Dinner Options

Traditional dinners offer a balanced mix of nutrients:

  • Balanced Macronutrients: A typical dinner includes proteins (e.g., chicken, fish, beans), carbohydrates (e.g., rice, pasta, potatoes), and vegetables. This combination ensures a balance of proteins, fats, and carbohydrates essential for health and energy.
  • Micronutrient Diversity: Dinners incorporate various vegetables and food groups, providing various vitamins, minerals, and antioxidants necessary for bodily functions and disease prevention.
  • Satiety and Satisfaction: Traditional meals’ mix of protein, fiber, and healthy fats promotes fullness and satisfaction, reducing the likelihood of overeating or unhealthy snacking later.

The Ethics of Marketing to Vulnerable Populations

Kellogg’s cereal-for-dinner suggestion raises an important ethical question about food companies’ responsibilities when they market to vulnerable people, especially those facing economic hardship. Businesses seek profit, but a moral aspect exists when marketing connects to issues like food insecurity.

Kellogg’s campaign, which promotes cereal as a cheap dinner, targets struggling families. While the company may frame this as helpful, it raises concerns about exploitation. When families must choose affordability overnutrition due to money problems, promoting a nutritionally weak meal replacement exploits their vulnerability for profit.

Kellogg’s may present its campaign as a solution to rising food costs, but its marketing to vulnerable people requires ethical review. Food companies must provide affordable food and promote healthy eating. They must avoid profiting from consumers’ financial problems. The cereal-for-dinner debate shows a need for ethical food marketing that values consumer well-being over profits.

Several ethical issues arise:

  • Exploiting Financial Hardship: Marketing cereal as dinner to families with money problems exploits their limited options. These families may choose the cheapest food, even if it lacks nutrition, just to eat. The company then profits from their hardship.
  • Misleading Messaging and Nutrition: Cereal can be part of a healthy diet, but it’s not a complete meal. Focusing on low cost without explaining its nutritional limits misleads people. This is worse for families with little access to fresh, healthy food. They may see cereal as an easy, cheap fix, unaware of its nutritional problems.
  • Responsibility to Promote Healthy Eating: Food companies should promote healthy eating, not just sell products. This becomes more important when marketing to vulnerable people instead of promoting a poor meal replacement.
  • Long-Term Health Problems: A diet heavy in processed cereal can cause long-term health problems, especially for children. Poor nutrition contributes to issues like obesity, diabetes, and development problems. Companies must consider these problems when marketing, especially to vulnerable groups.

Cereal for Dinner? 

The cereal-for-dinner controversy starkly reminds us of the widening gap between corporate messaging and the lived experiences of many Americans. It underscores the urgent need for a more nuanced and empathetic approach to addressing food insecurity and economic hardship.

While cost-saving measures are always welcome, they should not come at the expense of nutritional well-being and a genuine understanding of the struggles faced by families striving to make ends meet. The focus must shift from simplistic solutions to systemic changes that address the root causes of economic inequality and ensure access to affordable, nutritious food for all. 

Only then can we move beyond band-aid solutions and create a society where everyone has the opportunity to thrive, not just survive. The cereal-for-dinner debate should catalyze a broader conversation about corporate responsibility, economic justice, and the fundamental right to food security. It’s time to move beyond superficial solutions and address the underlying issues perpetuating food insecurity and financial hardship.

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Health

Man Left in Coma On Life Support After an Ingrown Hair on His Groin Turned Into Deadly Sepsis

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How often do we brush off life’s small irritations—a paper cut, a stubbed toe, or a stray ingrown hair? Most of the time, they’re harmless, just a fleeting discomfort. But what if one of these seemingly insignificant annoyances spiraled into something deadly? That’s exactly what happened to a young man whose ingrown hair turned into a ticking time bomb, leaving him in a coma and fighting for his life.

Sepsis, often called the “silent killer,” claims more lives than heart attacks, yet many people don’t even know what it is. This hidden menace lurks behind ordinary infections, waiting for the chance to unleash chaos on the body. In this case, a single follicle near his groin became the epicenter of a battle between life and death—offering a chilling reminder of how quickly things can escalate when it comes to our health.

How Ingrown Hair Led to a Medical Nightmare

It started as an ingrown hair, a common inconvenience that most people experience at some point. For 36-year-old Steven Spinale, however, what should have been a minor nuisance quickly became a life-threatening ordeal. The ingrown hair, located in a sensitive area near his groin, caused irritation that escalated into a localized infection. Instead of subsiding with time, the infection worsened, leaving him feverish, fatigued, and in mounting pain.

Unbeknownst to him, the infection had breached his bloodstream, triggering sepsis—a severe, potentially fatal response by the body to infection. Sepsis doesn’t merely attack the site of the infection; it unleashes a full-body assault, causing widespread inflammation and organ dysfunction. Left untreated, it can spiral out of control in hours. For this man, the infection’s progression was swift and unforgiving.

“He has been pretty sick for the last month or so and doctors couldn’t figure out what was wrong with him,” his sister Michelle Spinale shared on a GoFundMe page. “All they could figure out was he was bleeding internally from somewhere.” As he deteriorated rapidly, doctors faced a race against time to identify and contain the infection before it claimed his life. His case was a stark reminder of sepsis’s stealthy nature—it often masquerades as flu-like symptoms, making it easy to overlook until it’s too late. In this instance, a single infected hair follicle became the unlikely catalyst for a catastrophic medical emergency.

The Battle for Survival

When he arrived at the hospital, the man’s condition was critical. The infection had triggered full-blown sepsis, causing his body to shut down in ways that were both alarming and life-threatening. As his blood pressure plummeted and his organs struggled to function, doctors had no choice but to place him in a medically induced coma and connect him to life support. “He declined fast until he crashed and was put on life support,” his sister said. Machines now took over the tasks his failing body could no longer manage—breathing, pumping blood, and filtering waste.

Sepsis can be like a medical wildfire, consuming everything in its path if left unchecked. In his case, the infection’s rapid progression had given his immune system little chance to respond effectively. The medical team worked tirelessly to stabilize him, administering potent antibiotics to combat the infection and employing a range of interventions to prevent further organ damage. Each hour mattered; delays in treatment could mean the difference between life and death.

As his loved ones watched helplessly, the situation underscored the cruel unpredictability of sepsis. A seemingly minor health issue had spiraled into a fight for survival, testing the limits of modern medicine. For weeks, he remained in a precarious state, his life hanging by a thread as doctors battled to reverse the damage wrought by the infection. His case became a sobering reminder of the fragility of life and the devastating consequences of underestimating what can begin as a seemingly trivial health issue.

Recovery and Long-Term Impact

Emerging from the coma was only the beginning of a long and arduous road to recovery. After weeks on life support, the man’s body had endured immense trauma. While the immediate threat of sepsis had been quelled, the damage left behind was significant. Recovery from such an ordeal often comes with a steep price—physically, emotionally, and financially.

Physically, his body bore the scars of the fight for survival. Sepsis often leads to complications like tissue damage, organ dysfunction, or even amputation in severe cases. For him, the aftermath included weakened muscles, persistent fatigue, and a long rehabilitation process. Simple tasks that once felt effortless now demanded great effort, a daily reminder of how close he had come to losing his life.

Emotionally, the toll was just as profound. Survivors of sepsis often grapple with post-traumatic stress, depression, and anxiety. The fear of another health crisis loomed large, making even minor health issues a source of dread. Financially, the cost of life-saving treatments, prolonged hospital stays, and rehabilitation added another layer of difficulty, leaving his family struggling to manage the expenses.

Yet, amidst the challenges, there was also gratitude—gratitude for the doctors who fought tirelessly to save him, for the support of loved ones, and for a second chance at life. His story serves as both a warning and a testament to resilience, highlighting the importance of vigilance with health and the incredible capacity of the human body to recover, even against overwhelming odds.

@michellebell111

Drs make mistakes. Steven couldn’t be moved out of the room due to him crashing each time so certain tests couldn’t take place that should have in order to say he was brain dead. Thank god we didn’t pull the plug. #lifesupport #coma #wakingupfromacoma #foryoupage #miracle #intubated #drsmakemistakes #ingrownhair #medical #donorlist

♬ original sound – UrsulaRoets

The Hidden Dangers of Neglecting Minor Infections

This harrowing experience underscores a critical lesson: no health issue is too small to warrant attention. What starts as a minor infection, like an ingrown hair, can quickly spiral into a life-threatening condition if left unchecked. In the case of sepsis, the danger lies in its stealth. It often mimics flu-like symptoms—fever, chills, rapid heart rate—making it easy to dismiss until it’s too late.

Sepsis affects millions of people worldwide each year, with a mortality rate that rivals some of the deadliest diseases. Yet, public awareness of this “silent killer” remains startlingly low. Early detection is key to survival, as every hour without treatment increases the risk of fatality. Knowing the warning signs—extreme fever, confusion, rapid breathing, and a feeling of impending doom—can save lives.

Beyond recognizing the signs, prevention plays a crucial role. Basic hygiene, prompt treatment of minor wounds, and paying attention to unusual symptoms can dramatically reduce the risk of infections turning deadly. Health experts also emphasize the importance of not delaying medical care when something feels off. As this man’s story demonstrates, even a seemingly insignificant health issue can escalate with devastating speed, making vigilance and timely action lifesaving measures.

His ordeal serves as a wake-up call for everyone to prioritize their health and seek medical attention when necessary. It’s a sobering reminder that health is fragile, and even the smallest lapses can have profound consequences. The body’s resilience is remarkable, but it’s our responsibility to give it the care and attention it deserves.

A Powerful Reminder of Health’s Fragility

This man’s story is more than a cautionary tale—it’s a stark reminder of how life can change in an instant. What began as a small ingrown hair led to a battle against a relentless and often underestimated enemy: sepsis. His journey from a seemingly minor infection to the brink of death highlights the importance of vigilance, early detection, and the power of modern medicine.

Sepsis may not dominate headlines, but its impact is devastating, claiming millions of lives globally each year. It’s a silent predator, often overlooked until it’s too late. This story underscores why we must remain attentive to even the smallest changes in our health. Small infections, when ignored, can escalate into life-threatening crises, and the cost of inaction can be irreversible.

While the man’s ordeal was harrowing, it also serves as a beacon of hope and resilience. Thanks to timely medical intervention and his determination to recover, he was able to pull through. His experience urges all of us to take our health seriously, to listen to our bodies, and to never dismiss what may seem like minor discomforts. After all, it’s often the smallest things that have the power to change everything.

Featured image via Michelle Spinale, GoFundMe

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